The sequence–structure–function relationship of intrinsic ERα disorder
Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08400-1
Serine 118 phosphorylation drives conformational changes through the disruption of hydrophobic interactions between aromatic-rich clusters, showing how hydrophobic mutations can restore oestrogen receptor-mediated transcription.
Author Of article : Sichun Yang
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