Skin disease patients show response to targeted treatment

Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a chronic inflammatory skin condition of the skin, hair, nails, mouth and genitals. They described their findings in a study recently published in the Journal of Clinical Investigation that described their first-in-human, phase 2 clinical trial. The researchers identified unique molecular and cellular changes in the skin with lichen planus, particularly an overactive immune response involving specific…
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