Home Science Saturation genome editing-based clinical classification of BRCA2 variants
Science - 1 week ago

Saturation genome editing-based clinical classification of BRCA2 variants

Saturation genome editing-based clinical classification of BRCA2 variantsdoi:10.1038/s41586-024-08349-1

CRISPR–Cas9-based saturation genome editing in a humanized mouse embryonic stem cell line was used for comprehensive functional characterization of single nucleotide variants in a region of BRCA2, and shows good agreement with existing variant classifications and high predictive power.

Author Of article : Shyam K. Sharan

Read full article

Leave a Reply

Your email address will not be published. Required fields are marked *

Check Also

Human Arms Keep Growing an Extra Artery, And Here’s Why

Evolution is a mysterious thing. humans msft content Author Of article : Mike McRae Read f…