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Science - January 8, 2025

Host metabolism balances microbial regulation of bile acid signalling

Host metabolism balances microbial regulation of bile acid signalling

Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08379-9

A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.

Author Of article : Frank C. Schroeder

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