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β-C−H bond functionalization of ketones and esters by cationic Pd complexes

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β-C−H bond functionalization of ketones and esters by cationic Pd complexes

Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08281-4

Diverse methyl β-C−H functionalizations of ketones and esters are enabled by cationic Pd(II) complexes with MPANA ligands, offering access to spirocyclic and fused ring systems through enhanced catalyst–substrate affinity.

Author Of article : Jin-Quan Yu

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